Home Medication antibacterial
Home Medication antibacterial

piperacilline/tazobactam*

J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01C - Beta-Lactam Antibacterials, Penicillins -> J01CR - Combinations Of Penicillins, Incl. Beta-Lactamase Inhibitors -> J01CR05 - Piperacillin And Enzyme Inhibitor
Administration category: Free Medicine group: antibacterial File parts: piperacilline tazobactam Brand name: Tazocin

Safety margins

≥ 18 years
Weight ROA Dosage
ROA:
 iv 		Dosage:
 4000/500mg 4 dd
ROA:
 iv 		Dosage:
 16000/2000mg continuous per 24 hours
Comments:

Bij continue infusie eerst 4000/500 mg oplaaddosering eenmalig.

Standard dosages

Weight ROA Load Dosage
ROA:
 iv 		Load:
 4000/500mg 		Dosage:
 16000/2000mg continuous per 24 hours

Kidney function

≥ 18 years
ROA GFR Dosage Interval Comments
ROA: iv
GFR:
 30 - 50 		Dosage:
 4000/500 		Interval:
 8 Hours 		Comments:
 Continue infusie: Oplaad 4000/500 mg iv, direct aansluitend vervolgen met 12000/1500 mg continue infusie per 24 uur.
GFR:
 10 - 30 		Dosage:
 4000/500 		Interval:
 12 Hours 		Comments:
 Continue infusie: Oplaad 4000/500 mg iv, direct aansluitend vervolgen met 8000/1000 mg continue infusie per 24 uur.
Renal elimination: piperacilline 68 %, tazobactam 80%
Dosage: dependent on kidney function

Renal function-replacement therapy

CAPD: iv 4000/500 mg pip-tazo elke 12 uur

Hemo dialysis: iv 4000/500 mg pip-tazo elke 12 uur, na elke dialyseperiode een extra dosis van 2000/250 mg pip-tazo

CAV / VVHD: aanpassing van de dosering is niet noodzakelijk

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-502191.4
Updated: 01/27/2025 - 12:11
Status: Published

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